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Ineran
Hormonal
(Code: 0026-0004)

Price:u$d 14,72

Synthetic hormone vasopressor or antidiuretic action.
COMPOSITION
Occitoxin 10 UI/mL.

INERAN is Occitoxin highly purified, obtained by synthesis of the original active ingredient, extracted from the posterior lobe of the pituitary gland of domestic animals for slaughter.
INERA is an aqueous solution for injection containing the equivalent of 10 USP units of 0.2 Occitocina less vasopressor action units per mL of solution. It has no antidiuretic activity.

Bioactivity:
INERA acts directly on the smooth muscle of the uterus in all species, producing synchronous rhythmic contractions in it.
It is shown that in certain animal species, the cervix usually do not respond with contraction to the effects of Occitoxin.

The degree of uterine activity induced by the effects of occitoxin depends largely on the stage of the reproductive cycle in which the animal is placed at the time of administration.
The level of estrogen and progesterone in different stages of pregnancy, acting as the primary control mechanism occitoxin activity on the uterine musculature.
During the early stage of pregnancy the uterus is relatively insensitive to the action of occitoxin to increase as the pregnancy fails due to a close.

INERAN has a strong activity in relation to lower milk and its effect galactogogue. The mechanism by which the discharge is produced from milk by the mammary gland is still unknown, but presumably the occitoxin acts directly on certain elements of the smooth muscle in the mammary gland such as myoepithelial cells surrounding establishing the alveoli of the gland. One effect it occitoxin is found for the drug's ability to effectively promote milk letdown

DOSAGE

Dosing Guidance:
Treatment should continue following the instructions in the table of doses, or until the desired effect, subject to the routes and frequencies expressed in the dosing table. It is suggested to begin with the lower dose range and if necessary repeat the treatment.

Dosage Chart Guidance:
• Dog: 5-25 IU IM / 2-10 UllM EV / EV - Increased contractions: 1-5 IU SC / IM
Primary inertia: 5-20 IU IM / EV
Uterine prolapse, manual reduction: 5-20 IU IM

• Cat: 5-10 IU IM / EV 1-10 IU IM / EV
• Cow: 75-100 IU IM / EV 10-20 IU IM / EV
Increased contractions: 30 IU IM.
Repeat at 30 'if necessary.
• Mare: 75 to 100 IU IM / EV 10-20 IU IM / EV
Increased contractions: 20 IU IM
Induction of Labor: 80 to 100 IU diluted in Sc
Na Cl EV Slow drip to effect.
Retained placenta: 30-40 IU IM every 60 to 90 '.
Uterine infections: 20 IU IM 3-4 times daily for 2-3 days.

• Swine: 30-50 IU IM / EV 5-20 IU IM / EV
Increased contractions: 10 IU IM.
Repeat at 30 'if necessary.
• Sheep: 30-50 IU IM / EV 5-20 IU IM / EV
Retention of placenta: 10-20 IU IM.

ADMINISTRATION

- For obstetric use, the occitocina may be administered intravenously, intramuscularly or subcutaneously, under aseptic conditions appropriate.
- To achieve a rapid effect on the stimulation of milk letdown, the intravenous via is most appropriate.

- After intravenous administration, the drug acts on the uterine musculature immediately. Intramuscularly the effect is present between 3-5 minutes.
- In dogs, the duration of the effect of the drug, after being applied via EV - IM / SC is 13 to 20 minutes respectively.
- Small amounts of the drug can cross the placental barrier and therefore the fetal circulation. This effect does not cause depression sometime erratic on the fetus.

OVERDOSAGE

- The effect of overdose depends on the state of the uterus and the fetal position. Hypertonic or tetanic contractions may occur, causing an abrupt delivery, uterine rupture, fetal injury or death.
- Water intoxication can manifest itself, if large doses are administered occitoxyn accompanied by the administration of free-flowing liquid.

ADMINISTRATION

IM, EV Injectable

PRESENTATION

Vials containing 50 mL of sterile injectable solution synthetic Occitocina 10 IU / mL.

OBSERVATIONS

INERAN is indicated in relation to its action on uterine muscle in the following tables:
- Inducing labor.
- Accelerate the normal labor, or reverse a state of uterine inertia.
- Evacuation to lochia postpartum and / or retained placenta.
- Uterine contraction and rehabilitation after a Caesarean operation and control of uterine bleeding.
- Promotion of the letdown on a gland in appropriate physiological conditions. Optimizing the involution of the uterus after birth large fetuses.

CONTRAINDICATIONS

Do not use in dystocia due to poor box fetal presentation, until you have corrected the wrong position.

PRECAUTIONS:
- The occitoxyn effect is a powerful drug, which must be administered under medical prescription and control.
- For use prior to delivery, must wait for full dilation of the cervix in a physiological or by administering estrogen therapy before occitoxyn.

WARNINGS:
- Do not administer to animals in a state of hypocalcemia and / or severe hypoglycemia.
- Do not mix in the same vial or syringe with any other compound outside it.
- Do not ingest. Keep out of reach of children.
- Keep the product from 4 to 25 º C, protected from light, dry and hygienic. The product may also be stored at 2-8 ° C (not freezer).
- Check the Radiator and inviolability of the product and its storage and preservation conditions prior to use are adequate.
- The warning suggested dose in all cases are at the discretion of the veterinarian is acting.

SIDE EFFECTS:
Lacks at doses and frequencies indicated. There have been no hypersensitivity reactions to drugs.

RESTRICTIONS:
Overdose:
- The effect of overdose depend on the state of the uterus and the fetal position. Hypertonic or tetanic contractions may occur, causing an abrupt delivery, uterine rupture, fetal injury or death.
- Water intoxication can manifest itself, if large doses are administered occitoxyn accompanied by the administration of free-flowing liquid.

Presentation: x 50 ml.
Action
Action: Hormonal
  • Quantity: 
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