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Acuprin
Nutricional Supplements
(Code: RCH-0029)

Price:u$d 12,80

Nutritional supplement indicated for zinc and copper deficient diets.
COMPOSITION
Zinc, Copper and L-Methionine

Original development of Richmond Laboratories Veterinary Division Corp.

It is indicated to cure and prevent primary and secondary Cooper and/or Zinc deficiency.

DOSAGE:

• Animals under 200 kg: 2 ml total dose

• Animals over 200 kg: 3 ml total dose

Maximum dose: 5 ml

• Young bulls, heifers, bulls and cows: 4 ml

Maximum dose: 10 ml

These doses must be administered both for treatment and prevention, regardless the species, sex, age, breed and category of the animal or productive system.

• Strategic supplementation

- It is used in pregnant animals between the 6th and 7th month of gestation (indicated to supplement fetal deficiencies).

- It is used in postpartum treatment (45 to 60 days after parturition) to restore the blood levels before the following service.

- It is used in calves when they are 2 or 3 months old or before their first grazing. Another dose should be administered when the animals are between 6 and 9 months old.

• Systematic supplementation

- It can be administered systematically every 3 to 6 months to maintain the serum levels of zinc and copper.

- For the treatment of bovine foot rot or insidious keratoconjunctivitis, a dose of Acuprin can be administered and then repeated 30 to 60 days after the first application.

Sheep:

- It can be administered 4 to 6 weeks before parturition, and then treatment can be repeated after parturition.

• Copper poisoning

- Sheep are highly susceptible to copper toxicity. The following symptoms can be observed in case of acute poisoning: weakness, shaking, exhaustion, anorexia, hemoglobinury, jaundice and nasal hemorrhage. In case of overacute poisoning the following can be observed: respiratory deficiency, shock and sudden death

- In case of acute poisoning, medication must be discontinued immediately. Affected animals must be treated symptomatically (corticoids, antihistamines, bronchodilatators, etc)

• In order to avoid treating animals with hypercoppremia, the following precautions must be taken:

- Gather information about the animals anamnesis if the origin of the animals to be treated is unknown.

- If no medical information is available, inoculate the animals 60 days after receiving them.

- Observe the animals for copper-related deficiencies.

ADMINISTRATION:

Ready to use sterile SC injectable emulsion.

PRESENTATION:

ACUPRIN 500 ml bottle. Multidose bottle.

OBSERVATION:

ACUPRIN prevents and reverses physiopathologic diseases and metabolic imbalances such as:

• Nutritional anestrous.

• Lacking infertility syndrome

• Abortions

• Placental retention due to malnutrition

• Embryo absorption

• Sub clinical mastitis

• Cystic and polycystic ovaries

• Heat repetition

• Peri partus death

• Metritis

These are some of the secondary symptoms caused by the lack of zinc or copper in the diet.

Copper and zinc are essential cofactors for the activation of important enzymes that initiate plenty of intracellular metabolic functions.

ACUPRIN is used in low and poor fields when the soil has an alkaline pH and/or the water has a high concentration of free or combined sulphates and/or when there is molybdenum in the soil.

Sulphates and molybdenum tend to chelate copper and zinc in plants and/or at intraruminal level, impeding the animal to fulfill its nutritional need for zinc and copper. This leads to a state of clinical and/or subclinical deficiency that has visible signs and symptoms, such us, hyperkeratosis and parakeratosis in cattle and pigs with localized or diffuse depilation and pruritus, acromotriquia (faded haircoat), anorexia, diarrhea and catharsis; and it may end up in anorexia and death.

Other symptoms that show keratinization disorders or epithelial fragility are foot rot and insidious keratoconjunctivitis in cattle.

It improves spermatogenesis in bulls; it prevents osteomalasia and rachitis.

It promotes osseous and muscular development and growth, increasing the animals' cellular and humoural defenses and it increases nutritional conversion, therefore increasing production parameters.

It can be used in cattle, sheep and pigs regardless of breed, age, sex and productive condition.

CONTRAINDICATED:

- Do not administer more than 5 ml per application spot.

- The product has to be administered subcutaneously so as to ensure the depot effect and bioavailability of the product.

- Shake before use until the product is resuspended.

- Don't exceed indicated doses, especially in young animals and sheep.

- Do not eat. Keep out of reach of children.

- Doses and frequency of administration are to be determined by a veterinarian.

- Keep between 10 and 30º C, in the shade, in a clean place.

- Check the integrity of the security seal before using the product.

- Keep the conditions of asepsis and antisepsis before and during administration.

- Do not mix the product with other substances (antibiotics, anti-inflammatories, anesthetics, etc) in the syringe or in any other container. Consult a veterinarian before using the product.

- Recyclable container. Destroy after use. Do not contaminate the environment.

This product should be applied 30 days after the animals are vaccinated (regardless of the type of vaccine administered) or subjected to tuberculin tests. Use with particular care in dairy cattle because this breed is genetically sensitive.

COLLATERAL EFFECTS:

Some animals may show yielding and/or localized pain and inflammation in the inoculation spot. In other cases, there may be suppuration in the injection spot.

These symptoms do not interfere with the absorption or effectiveness of the product and these symptoms disappear without any kind of treatment in 7 days or less.

RESTRICTION:

The following restrictions are expressed according the rules of SENASA about long acting products with selenium, cooper and zinc included on its formulation.

There should be 30 days since the last treatment and the slaughter time to human consumption or industrialization.

Milk of treated animals must not be destined to human consumption or industrialization before 30 days from the last treatment.

Presentation: x 500 ml.
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